COMPARATIVE EVALUATION OF SEQUENTIAL INTRAOPERATIVE USE OF WHOLE BLOOD FOLLOWED BY BRILLIANT BLUE VERSUS CONVENTIONAL BRILLIANT BLUE STAINING OF INTERNAL LIMITING MEMBRANE IN MACULAR HOLE SURGERY
| Autor: | Preethi Sridharan, Meenakshi Thakar, Neha Goel, Richa Pyare, Basudeb Ghosh, Anisha Seth, Supriya Arora |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Intra operative genetic structures Visual Acuity Endotamponade Basement Membrane Comparative evaluation 03 medical and health sciences 0302 clinical medicine Prone Position medicine Humans Coloring Agents Macular hole Intraocular Pressure Aged Whole blood Intraoperative Care Staining and Labeling business.industry Internal limiting membrane Benzenesulfonates Epiretinal Membrane General Medicine Middle Aged Retinal Perforations medicine.disease Staining Surgery Ophthalmology Blood 030221 ophthalmology & optometry Female business Tomography Optical Coherence 030217 neurology & neurosurgery |
| Zdroj: | Retina. 36:1463-1468 |
| ISSN: | 0275-004X |
| DOI: | 10.1097/iae.0000000000000948 |
| Popis: | To compare the structural and functional outcome of use of autologous heparinized whole blood before staining internal limiting membrane with brilliant blue (BB) versus conventional BB-assisted macular hole surgery.Sixty eyes of 60 patients were randomly divided equally in Group A (BB staining using whole blood) and Group B (conventional BB staining). Clinical assessment and spectral domain optical coherence tomography was done at baseline and 3 weeks, 6 weeks, 16 weeks, and 6 months postoperatively.Group A eyes had a significantly higher best-corrected visual acuity as compared with Group B postoperatively (P0.001,0.001, 0.004, 0.04 at 3, 6, 16 weeks, and 6 months). Inner segment/outer segment junction continuity was noted in greater number of eyes in Group A compared with Group B (P = 0.02, 0.002, 0.003, and 0.03 at 3, 6, 16 weeks, and 6 months). Eyes in Group A had significantly higher outer foveal thickness at 3 weeks (P = 0.001) and 6 weeks (P0.001) compared with Group B.Use of whole blood before staining internal limiting membrane with BB causes earlier and better visual rehabilitation postoperatively, which could be attributed to earlier photoreceptor regeneration as evidenced by inner segment/outer segment junction continuity and increase in outer foveal thickness. |
| Databáze: | OpenAIRE |
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