Formation of a cyclic tetrapeptide mimic by thermal azide-alkyne 1,3-dipolar cycloaddition
| Autor: | Martin R. Krause, Stefan Kubik, Richard Goddard |
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| Rok vydání: | 2010 |
| Předmět: |
Models
Molecular Azides Magnetic Resonance Spectroscopy Alkyne Peptides Cyclic Catalysis chemistry.chemical_compound Biomimetic Materials Polymer chemistry Materials Chemistry Organic chemistry chemistry.chemical_classification Tetrapeptide Molecular Structure Metals and Alloys Temperature General Chemistry Cycloaddition Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Cyclization Alkynes 1 3-Dipolar cycloaddition Ceramics and Composites Azide |
| Zdroj: | Chemical communications (Cambridge, England). 46(29) |
| ISSN: | 1364-548X |
| Popis: | Cyclodimerisation of an appropriate alpha,omega-difunctionalised precursor via thermal azide-alkyne 1,3-dipolar cycloaddition affords a cyclic pseudotetrapeptide whose conformation closely resembles that of a previously prepared analogue containing L-proline and 6-aminopicolinic acid subunits. |
| Databáze: | OpenAIRE |
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