Rare diseases of phosphate and calcium metabolism: Crossing glances between nephrology and endocrinology

Autor: Aurélia Bertholet-Thomas, Mélodie Mosca, Julie Bernardor, Sandrine Lemoine, Justine Bacchetta
Přispěvatelé: Centre de référence des maladies rénales rares Néphrogones [CHU-HCL, Lyon], Hôpital Femme Mère Enfant [CHU - HCL] (HFME), Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Physiopathologie, diagnostic et traitements des maladies osseuses / Pathophysiology, Diagnosis & Treatments of Bone Diseases (LYOS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital l'Archet, Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL), Université de Lyon, CarMeN, laboratoire
Rok vydání: 2021
Předmět:
Nephrology
X-linked hypophosphatemia
medicine.medical_specialty
Hypoparathyroidism
Hypoparathyroïdie
[SDV]Life Sciences [q-bio]
Endocrinology
Diabetes and Metabolism
Phosphate
030209 endocrinology & metabolism
Context (language use)
Nephrolithiasis
Kidney
urologic and male genital diseases
Hypophosphatémie liée à l’X
Phosphates
Lithiase
03 medical and health sciences
Hyperphosphatemia
Rare Diseases
0302 clinical medicine
Endocrinology
Calcium Metabolism Disorders
Internal medicine
medicine
Teriparatide
Humans
Hypercalciuria
Patient Care Team
Calcium metabolism
business.industry
Hyperparathyroidism
Phosphorus Metabolism Disorders
General Medicine
medicine.disease
3. Good health
[SDV] Life Sciences [q-bio]
Hyperparathyroïdie
medicine.anatomical_structure
030220 oncology & carcinogenesis
Phosphore
Rein
Calcium
Interdisciplinary Communication
business
medicine.drug
Zdroj: Annales d'Endocrinologie
Annales d'Endocrinologie, Elsevier Masson, 2020, 82 (1), pp.30-35. ⟨10.1016/j.ando.2020.12.005⟩
ISSN: 0003-4266
2213-3941
Popis: International audience; Rare diseases of phosphate/calcium metabolism correspond to a wide and heterogeneous spectrum of diseases. Recent knowledge in physiology and genetics has made it possible to better characterize them and to propose attractive therapeutic approaches based on the underlying pathophysiology. These diseases are often at the interface between nephrology and endocrinology. In this spirit of a multidisciplinary care, each specialty can bring its own critical point of view and its own specificities to improve patient care. The objective of this manuscript is to "read" with a nephrologist's point of view the main frameworks of diseases of phosphate/calcium metabolism, to illustrate the three crucial messages of nephro-protection sent to endocrinologists. First, calciuria must be interpreted both in absolute value (concentration hypercalciuria) and in ratio (flow hypercalciuria). Second, renal monitoring of therapies inducing hypercalciuria on kidneys with normal renal function (e.g. active vitamin D analogs or teriparatide) should be systematic. Last, hyperphosphatemia, often latent in hypoparathyroidism and pseudo-hypoparathyroidism, should be detected and at least benefit from dietary measures, in the context of Western diets rich in phosphate hidden in food additives.
Databáze: OpenAIRE
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