6-AZACYTIDINE - COMPOUND WITH WIDE SPECTRUM OF ANTIVIRAL ACTIVITY

Autor:	L Palchikovskaja, A. Fedchuk, T. Gridina, Olga Povnitsa, A Shalamay, Lozitskaya Rn, L. N. Nosach, N. S. Dyachenko, V. L. Zhovnovataya, V. Lozitsky, S. L. Rybalko, I. V. Alexeeva
Rok vydání:	2001
Předmět:	Drug Dose-Response Relationship Drug Chemistry media_common.quotation_subject Herpes Simplex Herpesvirus 1 Human General Medicine Pharmacology Antiviral Agents Biochemistry Virology Disease Models Animal Mice Drug development Influenza A virus Influenza Human Azacitidine Genetics Animals Humans Molecular Medicine Encephalitis Herpes Simplex Dna viral HeLa Cells media_common
Zdroj:	Nucleosides, Nucleotides and Nucleic Acids. 20:1147-1152
ISSN:	1532-2335 1525-7770
DOI:	10.1081/ncn-100002508
Popis:	6-azacytidine demonstrates activity against adenoviruses types 1, 2, 5. It inhibit synthesis of viral DNA and proteins. 6-AC shows antiherpetic and antiinfluenza action during experimental infection in mice. 6-AC is prospective for drug development as an antiviral substance with a wide spectrum of activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4990add57378f5c9a61a0b6e8d38aa https://doi.org/10.1081/ncn-100002508 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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