The efficacy and safety of percutaneous microwave coagulation by a new microwave delivery system in large hepatocellular carcinomas: four case studies

Autor:	Zhaocai Yu, Ying Huang, Xiaoming Si, Jie Shao, Wenchao Liu, Li Fan
Rok vydání:	2009
Předmět:	Adult Male Cancer Research medicine.medical_specialty Percutaneous Carcinoma Hepatocellular Physiology medicine.medical_treatment Physiology (medical) medicine Carcinoma Humans Microwaves business.industry Liver Neoplasms Cancer Microwave coagulation Middle Aged medicine.disease Ablation Clinical trial Catheter Ablation Female Radiology Tomography Delivery system Safety business Tomography X-Ray Computed
Zdroj:	International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 25(5)
ISSN:	1464-5157
Popis:	To demonstrate the efficacy and safety of percutaneous microwave coagulation treatment (PMCT) by a new microwave delivery system (Forsea Microwave) in large hepatocellular carcinomas (HCC) (or =5 cm).Four patients with 4 HCC lesions measuringor =6 cm in the greatest dimension underwent PMCT by means of the Forsea Microwave microwave delivery system. Final therapeutic efficacy was evaluated with dynamic computer tomography (CT) scans performed within one month after PMCT. During and after PMCT, patients' complaints and any abnormal physical signs were recorded for safety assay. CT or ultrasound scan (US) performed immediately after the treatment was used to detect acute complications related to the treatment. Repeated dynamic CT scans were performed every three to four months thereafter to detect local disease recurrence and/or other recurrences.Three of these patients achieved a complete ablation of the cancer nodules (two patients with two treatment sessions and one patient with three treatment sessions). One of these patients obtained a complete ablation of the cancer nodule with two treatment sessions except the lesion of portal vein tumour thrombus (PVTT). No obvious symptomatic complication was observed except abdominal pain during and after the treatment in two of these patients. All the patients remained asymptomatic and no recurrent tumour was observed during their follow-up (1-19 months).PMCT by the Forsea Microwave microwave delivery system could offer a satisfactory therapeutic effect and is applicable to the treatment of large HCC.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3ca267c2c0d6cc61b4c91a053213e5 https://pubmed.ncbi.nlm.nih.gov/19551547 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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