Genetic characteristics of 19 STRs in Chinese Uzbek ethnic and its phylogenetic relationships with other 24 populations
| Autor: | Yuxin Guo, Bofeng Zhu, Jiangang Chen, Chong Chen, Yuanyuan Wei, Yuling Mu, Xiaoye Jin, Wei Cui, Qian Dong, Tingting Kong |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
China Population Ethnic group Kazakh Biology Pathology and Forensic Medicine 03 medical and health sciences symbols.namesake 0302 clinical medicine Gene Frequency Ethnicity Humans Allele education Phylogeny education.field_of_study Polymorphism Genetic Phylogenetic tree DNA Fingerprinting Uzbek language.human_language 030104 developmental biology Bonferroni correction Genetics Population Evolutionary biology language symbols Microsatellite 030217 neurology & neurosurgery Microsatellite Repeats |
| Zdroj: | International journal of legal medicine. 132(3) |
| ISSN: | 1437-1596 |
| Popis: | Allelic frequencies and genetic polymorphisms of 19 short tandem repeats loci were investigated so as to provide more genetic data for forensic applications in Chinese Uzbek group; besides, we evaluated phylogenetic relationships of Uzbek group with other populations. All loci were observed to conform to Hardy-Weinberg equilibrium after Bonferroni's correction. Two hundred and nine alleles were identified in 212 unrelated healthy Uzbek individuals and their allelic frequencies ranged from 0.0024 to 0.5259. The cumulative discrimination power and cumulative probability of exclusion were 0.999999999999999999999996501 and 0.999999998759, respectively. The results of population differentiation comparison, principal component analysis, and phylogenetic tree revealed that Uzbek group had close relationships with Uyghur and Kazakh groups. |
| Databáze: | OpenAIRE |
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