Central wave reflection is associated with peripheral arterial resistance in addition to arterial stiffness in subjects without antihypertensive medication

Autor: Mika Kähönen, Antti Tikkakoski, Anna Tahvanainen, Heini Huhtala, Jenni Koskela, Jukka Mustonen, Antti Haring, Tiit Kööbi, Matias Wilenius, Ilkka Pörsti
Přispěvatelé: Lääketieteen yksikkö - School of Medicine, Terveystieteiden yksikkö - School of Health Sciences, University of Tampere
Rok vydání: 2016
Předmět:
Male
Hemodynamics
Blood Pressure
030204 cardiovascular system & hematology
0302 clinical medicine
Heart Rate
Medicine
030212 general & internal medicine
Pulse wave velocity
Aged
80 and over
medicine.diagnostic_test
Sisätaudit - Internal medicine
Models
Cardiovascular
Stroke volume
Middle Aged
Arterial stiffness
Impedance cardiography
medicine.anatomical_structure
Hypertension
Cardiology
Female
Cardiology and Cardiovascular Medicine
Research Article
Adult
medicine.medical_specialty
Biolääketieteet - Biomedicine
Manometry
Systemic vascular resistance
Pulse Wave Analysis
Cardiography
Impedance
03 medical and health sciences
Young Adult
Age Distribution
Vascular Stiffness
Predictive Value of Tests
Internal medicine
Heart rate
Humans
Central wave reflection
Sex Distribution
Aged
Plethysmography
Whole Body
business.industry
Augmentation index
Stroke Volume
medicine.disease
Blood pressure
Multivariate Analysis
Vascular resistance
Linear Models
Vascular Resistance
business
Zdroj: BMC Cardiovascular Disorders
ISSN: 1471-2261
Popis: Background Augmentation index, a marker of central wave reflection, is influenced by age, sex, height, blood pressure, heart rate, and arterial stiffness. However, the detailed haemodynamic determinants of augmentation index, and their relations, remain uncertain. We examined the association of augmentation index with vascular resistance and other haemodynamic and non-haemodynamic factors. Methods Background information, laboratory values, and haemodynamics of 488 subjects (239 men, 249 women) without antihypertensive medication were obtained. Indices of central wave reflection, systemic vascular resistance, cardiac function, and pulse wave velocity were measured using continuous radial pulse wave analysis and whole-body impedance cardiography. Results In a regression model including only haemodynamic variables, augmentation index in males and female subjects, respectively, was associated with systemic vascular resistance (β = 0.425, β = 0.336), pulse wave velocity (β = 0.409, β = 0.400) (P
Databáze: OpenAIRE
Externí odkaz: