Sequential occurrence of anti-glomerular basement membrane disease 9 years after anti-neutrophil cytoplasmic antibody-associated vasculitis
| Autor: | Moon Ho Leung, Pui Shan Julia Chan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty 030232 urology & nephrology Disease Case Reports Anti-Glomerular Basement Membrane Disease urologic and male genital diseases Microbiology 03 medical and health sciences 0302 clinical medicine medicine Goodpasture's syndrome Rapidly progressive glomerulonephritis 030212 general & internal medicine Anti-neutrophil cytoplasmic antibody Basement membrane biology business.industry medicine.disease Infectious Diseases medicine.anatomical_structure Immunology biology.protein Parasitology Antibody business Vasculitis |
| Zdroj: | Oxford Medical Case Reports |
| ISSN: | 2053-8855 |
| Popis: | We report a case of 63-year-old Chinese man, having a history of anti-myeloperoxidase (MPO) antibody anti-neutrophil cytoplasmic antibody (ANCA)-associated pulmonary-renal syndrome 9 years ago, presented with second episode of rapidly progressive glomerulonephritis (RPGN) and alveolar haemorrhage compatible with anti-glomerular basement membrane (GBM) disease. In first presentation, his anti-GBM antibody was negative. This time, anti-MPO antibody was negative, but anti-GBM antibody was positive. The long interval of sequential development of anti-GBM disease after ANCA-associated vasculitis in this patient may provide clues to the potential immunological links between these two distinct conditions. Clinicians should be aware of such double-positive association. |
| Databáze: | OpenAIRE |
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