Nebulized Ipratropium bromide protects against tracheal and bronchial secretion during bronchoscopy: A randomized controlled trial
| Autor: | Fengming Luo, Yanlin Zhang, Faping Wang, Felix J.F. Herth, He Zheng, Xiang Zhang, Yunxiao Luo, Hui Zhu, Jingyu Shi, Hui Mao |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Bodily Secretions bronchoscopy Premedication ipratropium bromide Bronchi Ipratropium bromide Placebo law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Bronchoscopy Double-Blind Method law Administration Inhalation Medicine Humans 030212 general & internal medicine Adverse effect medicine.diagnostic_test business.industry Ipratropium Nebulizers and Vaporizers General Medicine Clinical Trial/Experimental Study Middle Aged Bronchodilator Agents Trachea secretion 030220 oncology & carcinogenesis Anesthesia randomized controlled trial Female Complication business Airway medicine.drug Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Background: Anticholinergic administration prior to flexible bronchoscopy has been investigated, but studies have not yielded consistent results. Methods: Patients were randomized 1:1 to receive nebulized 4 ml ipratropium bromide (1 mg, n = 125) or placebo (n = 125) for 15 minutes as premedication, 20 to 40 minutes before bronchoscopy. Airway secretions, bleeding, patient discomfort, procedure time, and procedure-related adverse events were compared between the groups. Results: Nebulized ipratropium bromide prior to bronchoscopy could reduce airway secretions and patient discomfort (P = .02; P |
| Databáze: | OpenAIRE |
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