Quantitative analysis of left ventricular strain using cardiac computed tomography
| Autor: | Waldemar Hosch, Hans-Ulrich Kauczor, Hugo A. Katus, Evangelos Giannitsis, Derliz Mereles, Christian Galuschky, Grigorios Korosoglou, Daniel Stapf, Felix Schulz, Nina Hofmann, Georg Schummers, Stefan E. Hardt, Sebastian J. Buss |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Cardiac resynchronization therapy Sensitivity and Specificity Ventricular Dysfunction Left Elastic Modulus Internal medicine Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging End-systolic volume Aged Heart Failure Ejection fraction Cardiac Vein medicine.diagnostic_test business.industry Reproducibility of Results Echogenicity Magnetic resonance imaging General Medicine Image Enhancement medicine.disease Echocardiography Evaluation Studies as Topic Heart failure Cardiology Anisotropy Elasticity Imaging Techniques End-diastolic volume Stress Mechanical Tomography X-Ray Computed business |
| Zdroj: | European Journal of Radiology. 83:e123-e130 |
| ISSN: | 0720-048X |
| Popis: | To investigate whether cardiac computed tomography (CCT) can determine left ventricular (LV) radial, circumferential and longitudinal myocardial deformation in comparison to two-dimensional echocardiography in patients with congestive heart failure.Echocardiography allows for accurate assessment of strain with high temporal resolution. A reduced strain is associated with a poor prognosis in cardiomyopathies. However, strain imaging is limited in patients with poor echogenic windows, so that, in selected cases, tomographic imaging techniques may be preferable for the evaluation of myocardial deformation.Consecutive patients (n=27) with congestive heart failure who underwent a clinically indicated ECG-gated contrast-enhanced 64-slice dual-source CCT for the evaluation of the cardiac veins prior to cardiac resynchronization therapy (CRT) were included. All patients underwent additional echocardiography. LV radial, circumferential and longitudinal strain and strain rates were analyzed in identical midventricular short axis, 4-, 2- and 3-chamber views for both modalities using the same prototype software algorithm (feature tracking). Time for analysis was assessed for both modalities.Close correlations were observed for both techniques regarding global strain (r=0.93, r=0.87 and r=0.84 for radial, circumferential and longitudinal strain, respectively, p0.001 for all). Similar trends were observed for regional radial, longitudinal and circumferential strain (r=0.88, r=0.84 and r=0.94, respectively, p0.001 for all). The number of non-diagnostic myocardial segments was significantly higher with echocardiography than with CCT (9.6% versus 1.9%, p0.001). In addition, the required time for complete quantitative strain analysis was significantly shorter for CCT compared to echocardiography (877±119 s per patient versus 1105±258 s per patient, p0.001).Quantitative assessment of LV strain is feasible using CCT. This technique may represent a valuable alternative for the assessment of myocardial deformation in selected patients with poor echogenic windows and general contraindications for magnetic resonance imaging. |
| Databáze: | OpenAIRE |
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