Oral midazolam is a safe and effective premedication in adult outpatients undergoing brachytherapy for cancer cervix under general anaesthesia: A prospective randomised, double blind placebo-controlled study
| Autor: | Manisha Hemrajani, Meenakshi Saxena, Rakhi Bansal, Anjum S Khan Joad |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Sedation medicine.medical_treatment Brachytherapy Placebo-controlled study Perioperative Brief Communication Surgery lcsh:RD78.3-87.3 Route of administration Anesthesiology and Pain Medicine lcsh:Anesthesiology Anesthesia medicine Anxiety Premedication General anaesthesia medicine.symptom business |
| Zdroj: | Indian Journal of Anaesthesia, Vol 59, Iss 7, Pp 437-439 (2015) Indian Journal of Anaesthesia |
| ISSN: | 0019-5049 |
| Popis: | Anxiety in response to impending surgery is a common emotional phenomenon, but it also leads to perioperative physiological and psychological changes.[1] The major goal of pre-medication is to allay anxiety. An ideal pre-medicant should have a non-invasive route of administration, rapid and reliable onset, rapid elimination, consistent and predictable results and good patient acceptance. At the same time, it should also be free of side effects like haemodynamic instability, respiratory obstruction and delayed recovery.[2] Oral midazolam fulfills many of these characteristics. It has been extensively evaluated in children and is considered the gold standard pre-medicant for this age group but data regarding its use in adults is scarce.[3] This study was planned to evaluate the role of oral midazolam in adult females undergoing intracavitary cervical implantation for brachytherapy under general anaesthesia. Evaluation of sedation and anxiolysis was our primary objective. Safety profile in terms of haemodynamic stability, respiratory depression and recovery time, and amnestic effects were also assessed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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