How strong is the evidence that it is possible to get SARS‐CoV‐2 twice? A systematic review
| Autor: | Aqsa Mumtaz, Muhammad Khawar Sana, Larabe Farrukh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty recurrence Adolescent Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 030106 microbiology Population Psychological intervention Review Disease re‐infection medicine.disease_cause SARS‐CoV‐2 Young Adult 03 medical and health sciences Virology medicine Humans Intensive care medicine education Aged risk Coronavirus Aged 80 and over Covid‐19 education.field_of_study SARS-CoV-2 business.industry COVID-19 Middle Aged After discharge 030104 developmental biology Infectious Diseases Reinfection Female business Re infection |
| Zdroj: | Reviews in Medical Virology |
| ISSN: | 1099-1654 1052-9276 |
| DOI: | 10.1002/rmv.2203 |
| Popis: | Summary With a large number of coronavirus disease 2019 (Covid‐19) patients being discharged from hospital with negative test results for SARS‐CoV‐2, it has been reported that several recovered cases tested positive after discharge (re‐positive, RP). This finding has raised several important questions for this novel coronavirus and Covid‐19 disease. In this review, we have discussed several important questions, including: (1) Can the virus re‐infect recovered individuals? (2) What are the possible causes of the re‐positive reverse transcriptase‐polymerase chain reaction (RT‐PCR) test in recovered patients? (3) What are the implications of these re‐positive cases concerning the spread of the virus? Understanding how recovery from Covid‐19 confers immunity to decrease the risk of re‐infection is needed to inform current efforts to safely scale back population‐based interventions, such as physical distancing. We have also described what is currently known about the immune response to Covid‐19, highlighted key gaps in knowledge, and identified opportunities for future research. Overall, the quality of the evidence is poor and we describe the features that should be described for future cases. |
| Databáze: | OpenAIRE |
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