Catecholamine and cyclic nucleotide response of sheep to the injection of Clostridium welchii type D epsilon toxin
| Autor: | H. J. Bertschinger, Maria S. G. Mülders, R. W. Worthington |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Microbiology (medical)
Blood Glucose medicine.medical_specialty Glycogenolysis Epinephrine Dopamine Bacterial Toxins Guanosine Biology medicine.disease_cause Microbiology Cyclase Clostridium welchii chemistry.chemical_compound Cyclic nucleotide Norepinephrine Catecholamines Internal medicine medicine Cyclic AMP Animals Cyclic GMP Clostridium Sheep Toxin General Medicine Adenosine Endocrinology chemistry Catecholamine medicine.drug |
| Zdroj: | Journal of medical microbiology. 12(4) |
| ISSN: | 0022-2615 |
| Popis: | Summary Injection of Clostridium welchii (C. perfringens) type D epsilon toxin into sheep caused large increases in catecholamine and cyclic adenosine 3′,5′-monophosphate levels and moderate increases in cyclic guanosine 3′,5′-monophosphate levels. Haemoconcentration also occurred. It is suggested that a rapidly developing brain oedema is the stimulus for a release of catecholamines which in turn activates adenyl cyclase. The resulting rise in cAMP causes glycogenolysis and hyperglycaemia. |
| Databáze: | OpenAIRE |
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