Cognitive and behavioral trajectories in 22q11DS from childhood into adolescence: A prospective 6-year follow-up study
| Autor: | Jacob A. S. Vorstman, Henriette F. N. Swanenburg de Veye, Petra W.J. Klaassen, Gerben Sinnema, Frits A. Beemer, Sasja N. Duijff |
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| Rok vydání: | 2013 |
| Předmět: |
Male
22q11 Deletion Syndrome Adolescent Early adolescence Psychology Adolescent Psychology Child Child Behavior Disorders Developmental psychology Child Development Risk Factors Developmental and Educational Psychology Cognitive development Humans Cognitive deterioration Longitudinal Studies Prospective Studies Child Cognitive impairment Internal-External Control Follow up studies Cognition Adolescent Development Clinical Psychology Developmental trajectory Female Cognition Disorders Psychology Follow-Up Studies |
| Zdroj: | Research in Developmental Disabilities. 34:2937-2945 |
| ISSN: | 0891-4222 |
| DOI: | 10.1016/j.ridd.2013.06.001 |
| Popis: | Patients with 22q11DS are at risk of behavioral problems and cognitive impairment. Recent studies suggest a possible intellectual decline in 22q11DS children. To date it is unknown if cognitive development is related to the behavioral problems in 22q11DS. We studied 53 children with 22q11DS who underwent cognitive and behavioral assessments at 9.5 years (T1) and 15.3 years (T2). In about one third, IQ data obtained at 7.5 years (T0) were also available. Results showed that internalizing behaviors intensified while externalizing behaviors decreased. Simultaneously, in about a third a significant decline in IQ was found, which, surprisingly, was unrelated to the behavioral changes. It can be concluded that children with 22q11DS follow a unique developmental trajectory. Cognitive deterioration is severe in some but does not appear to predict behavioral problems in early adolescence. |
| Databáze: | OpenAIRE |
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