Operative and Therapeutic Advancements in Breast Cancer Metastases to the Brain
| Autor: | J. Dawn Waters, George Somlo, Reid Hoshide, Rahul Jandial |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Breast Neoplasms Neuroimaging Disease 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine medicine Humans Minimally Invasive Surgical Procedures Genetic Testing skin and connective tissue diseases Brain Neoplasms business.industry Incidence Neurooncology Brain Cancer medicine.disease Metastatic breast cancer 030220 oncology & carcinogenesis Female Immunotherapy Neurosurgery Primary breast cancer business 030217 neurology & neurosurgery |
| Zdroj: | Clinical Breast Cancer. 18:e455-e467 |
| ISSN: | 1526-8209 |
| Popis: | Patients with breast cancer are surviving longer as the state of the art for care advances. Because patients are surviving longer with primary breast cancer, the incidence of secondary metastatic disease has risen. Metastatic breast cancer to the brain was once thought to be universally fatal. While it is still quite lethal, its treatment after diagnosis is increasingly safe and effective. Critical progress has been made in understanding the interaction between breast metastases and the neural niche, neuroimaging of functional anatomy, minimally invasive image-guided brain surgery, characterizing subtypes of breast cancer based on molecular and genetic profiles, and individualized pharmaceuticals and immunotherapies. In this review, we discuss recent advances that have brought us to state-of-the-art management of metastatic breast cancer to the brain. |
| Databáze: | OpenAIRE |
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