Acute neutropenia decreases inflammation associated with murine vaginal candidiasis but has no effect on the course of infection
| Autor: | Adrian Russell, Robert Clancy, C. Allen Black, Fiona M Eyers, Margaret Dunkley, Kenneth W. Beagley |
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| Předmět: |
Neutropenia
Ratón Neutrophils Neutrophile Immunology Inflammation Microbiology Mice Vaginal disease medicine Vaginal candidiasis Animals Candida albicans Mycosis Candidiasis Vulvovaginal Mice Inbred C3H biology medicine.disease biology.organism_classification Infectious Diseases Acute Disease Parasitology Female medicine.symptom Fungal and Parasitic Infections |
| Zdroj: | Scopus-Elsevier Ken Beagley ResearcherID |
| Popis: | We have used a mouse model of vaginal candidiasis to determine the effect of neutrophil depletion on (a) the clearance of Candida albicans and (b) the degree of inflammation associated with infection. No differences in recoverable yeast number or rate of clearance were observed between normal and neutrophil-depleted mice; however, vaginal inflammation was significantly decreased in neutrophil-depleted animals. |
| Databáze: | OpenAIRE |
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