Disentangling outbreaks using whole-genome sequencing: concurrent multistate outbreaks of Salmonella Kottbus in Germany, 2017
Autor: | Christina Frank, Angelika Fruth, Sandra Simon, M. Borowiak, Julia Enkelmann, S. Gillesberg Lassen, A. von Laer, Raskit Lachmann, Kai Michaelis |
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Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Serotype Whole genome sequencing food-borne infections Veterinary medicine Salmonella salmonellosis Molecular epidemiology Epidemiology 030106 microbiology Outbreak Biology medicine.disease_cause molecular epidemiology 3. Good health 03 medical and health sciences 0302 clinical medicine Infectious Diseases Germany outbreaks Salmonella kottbus medicine ddc:610 030212 general & internal medicine 610 Medizin und Gesundheit |
Zdroj: | Epidemiology and Infection. 148 |
ISSN: | 1469-4409 0950-2688 |
Popis: | In June 2017, an outbreak of Salmonella Kottbus infection was suspected in Germany. We investigated the outbreak with whole-genome sequencing (WGS) and a case–control study. Forty-six isolates from 69 cases were subtyped. Three WGS clusters were identified: cluster 1 (n = 36), cluster 2 (n = 5) and cluster 3 (n = 3). Compared to controls, cluster 1 cases more frequently consumed raw smoked ham (odds ratio (OR) 10, 95% confidence interval (CI) 1.2–88) bought at supermarket chain X (OR 36, 95% CI 4–356; 9/10 consumed ham Y). All four cluster 2 cases interviewed had consumed quail eggs. Timely WGS was invaluable in distinguishing concurrent outbreaks of a rare Salmonella serotype. |
Databáze: | OpenAIRE |
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