Peptidoglycan pathways: there are still more!
| Autor: | Mohamed M. Elsebaei, Mariam Omara, Abdelrahman S. Mayhoub, Ahmed M. Helal, Ahmed M. Sayed |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.drug_class
General Chemical Engineering Antibiotics 02 engineering and technology General Chemistry Computational biology Biology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Bacterial protein chemistry.chemical_compound Antibiotic resistance Who recommendations chemistry medicine Peptidoglycan 0210 nano-technology |
| Zdroj: | RSC Advances. 9:28171-28185 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c9ra04518j |
| Popis: | The discovery of 3rd and 4th generations of currently existing classes of antibiotics has not hindered bacterial resistance, which is escalating at an alarming global level. This review follows WHO recommendations through implementing new criteria for newly discovered antibiotics. These recommendations focus on abandoning old scaffolds and hitting new targets. In light of these recommendations, this review discusses seven bacterial proteins that no commercial antibiotics have targeted yet, alongside their reported chemical scaffolds. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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