Characterization of microRNA and mRNA expression profiles in skin tissue between early-feathering and late-feathering chickens
| Autor: | Hua Li, Qinghua Nie, Xinzheng Jia, Ying Yang, Fang Guijun, Hui Yu, Shuwen Tan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Time Factors animal structures lcsh:QH426-470 lcsh:Biotechnology mRNAs Biology Skin tissues Transcriptome 03 medical and health sciences 0302 clinical medicine Feathering lcsh:TP248.13-248.65 Gene expression microRNA Genetics Animals RNA Messenger Epithelial cell differentiation Skin Sequence Analysis RNA Gene Expression Profiling food and beverages Feathers Phenotype Chicken Fold change Cell biology microRNAs lcsh:Genetics 030104 developmental biology Feather visual_art visual_art.visual_art_medium Late-feathering Chickens 030217 neurology & neurosurgery Biotechnology Research Article Signal Transduction |
| Zdroj: | BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018) BMC Genomics |
| ISSN: | 1471-2164 |
| Popis: | Background Early feathering and late feathering in chickens are sex-linked phenotypes, which have commercial application in the poultry industry for sexing chicks at hatch and have important impacts on performance traits. However, the genetic mechanism controlling feather development and feathering patterns is unclear. Here, miRNA and mRNA expression profiles in chicken wing skin tissues were analysed through high-throughput transcriptomic sequencing, aiming to understand the biological process of follicle development and the formation of different feathering phenotypes. Results Compared to the N1 group with no primary feathers extending out, 2893 genes and 31 miRNAs displayed significantly different expression in the F1 group with primary feathers longer than primary-covert feathers, and 1802 genes and 11 miRNAs in the L2 group displayed primary feathers shorter than primary-covert feathers. Only 201 altered genes and 3 altered miRNAs were identified between the N1 and L2 groups (fold change > 2, q value |
| Databáze: | OpenAIRE |
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