The Use of Antimicrobials in Italian Heavy Pig Fattening Farms
| Autor: | Lis Alban, Loredana Candela, Adriana Ianieri, Nicoletta Vitale, Francesca Giudici, E. Giacomini, Angelica Maggio, Nicoletta Formenti, Giovanni Santucci, M. Lazzaro, Antonio M. Maisano, Federico Scali, Giorgio Bontempi, Silvio Borrello, Sergio Ghidini, Matteo Tonni, Alberto Amicabile, Federica Guadagno, Jeroen Dewulf, Giovanni Loris Alborali, Giancarlo Belluzzi, Paolo Pasquali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) 040301 veterinary sciences 030106 microbiology DRUG-USE prudent use Biology BIOSECURITY Biochemistry Microbiology Article DDDAit 0403 veterinary science 03 medical and health sciences Animal science DDDvet Pharmacology (medical) Veterinary Sciences USAGE General Pharmacology Toxicology and Pharmaceutics HERDS AMU lcsh:RM1-950 ANIMALS Monitoring system swine 04 agricultural and veterinary sciences Antimicrobial mortality Confidence interval pig production Infectious Diseases Antimicrobial use Defined daily dose lcsh:Therapeutics. Pharmacology Herd |
| Zdroj: | Antibiotics, Vol 9, Iss 892, p 892 (2020) Antibiotics Volume 9 Issue 12 ANTIBIOTICS-BASEL |
| ISSN: | 2079-6382 |
| Popis: | Data on antimicrobial use (AMU) in heavy pig production (> 150 kg) are limited. The aim of this study was to investigate the AMU in this production. Data from 2015 were collected for 143 fattening farms. The AMU was estimated through a treatment index per 100 days (TI100) using the defined daily dose animal for Italy (DDDAit). When possible, a comparison with the European Medicines Agency&rsquo s defined daily doses for animals (DDDvet) was performed. The median TI100 was 10.7 (range, 0.2&ndash 49.5). Group treatments represented 94.6% of overall consumption. The AMU calculated using DDDAit and DDDvet were strongly correlated (&rho = 0.976 p < 0.001). The AMU was negatively correlated with injectables use (&rho = &minus 0.46, p < 0.001) and positively correlated with oral products (&rho = 0.21, p = 0.014), premixes (&rho = 0.26, p = 0.002), and mortality (&rho = 0.18 p = 0.027). Farm size was negatively correlated with AMU (&rho 0.29, p < 0.001). Smaller farms were more frequently above the median TI100 (odds ratio = 2.3, 95% confidence interval = 1.2&ndash 4.7), suggesting that they may have lower biosecurity and management standards. The results of this study should provide useful insights for the development of an Italian monitoring system. |
| Databáze: | OpenAIRE |
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