Multiple Cranial Nerve Palsies in Testicular Lymphoma: Report of a Case

Autor: M Falorni, Giovanni Orlandi, Michelangelo Mancuso, Luigi Murri, De Simone Paolo, Nicola Morelli, Cristina Frittelli, Simone Gallerini
Rok vydání: 2007
Předmět:
Zdroj: The Neurologist. 13:222-224
ISSN: 1074-7931
DOI: 10.1097/nrl.0b013e31805778e8
Popis: BACKGROUND Testicular lymphoma is an aggressive, extranodal, non-Hodgkin lymphoma, accounting for less than 10% of all testicular neoplasms and less than 1% of lymphoproliferative malignancies. A paraneoplastic syndrome has been reported and may precede diagnosis of testicular cancer. A delay in diagnosis results in more advanced stage at clinical presentation and resultant poor outcome. CASE SUMMARY We report here a case of testicular lymphoma associated with multiple cranial nerve palsies contributing to the diagnosis of an occult lymphoproliferative malignancy. CONCLUSIONS In elderly men, accurate urologic examination is mandatory, particularly when other malignancies have been ruled out, since timely diagnosis of testicular malignancy may allow successful treatment. Paraneoplastic syndromes secondary to extranodal malignancies should be always taken into account in the evaluation of patients with multiple nerve palsies with no apparent primary neurologic disease.
Databáze: OpenAIRE