Radiofrequency ablation for markedly incompetent perforators versus compression therapy in the management of post-phelebtic venous ulcers: A randomized controlled trial
| Autor: | Amr M. Elshafei, Ehab Saad, Amr Sameer, Tamer Khafagy, Hesham A. Sharaf El-Din, Mohamed A Abdelmaksoud, Mohamed S. Abdelgawad, Nshaat A. Elsaadany |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Radiofrequency ablation 030204 cardiovascular system & hematology 030230 surgery Varicose Ulcer law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Recurrence law Humans Medicine Radiology Nuclear Medicine and imaging Radiofrequency Ablation Wound Healing business.industry Reflux General Medicine Incompetent perforators Compression therapy Venous Valves Surgery Venous Insufficiency Catheter Ablation Venous reflux Cardiology and Cardiovascular Medicine business |
| Zdroj: | Vascular. 30:357-364 |
| ISSN: | 1708-539X 1708-5381 |
| Popis: | Background Venus ulcers developed mainly due to reflux of incompetent venous valves in perforating veins. Patients and methods In this randomized controlled trial, 119 patients recruited over two years, with post-phelebtic venous leg ulcers, were randomly assigned into one of two groups: either to receive radiofrequency ablation of markedly incompetent perforators (Group A, n = 62 patients) or to receive conventional compression therapy (Group B, n = 57 patients). Follow-up duration required for ulcer healing continued for 24 months post randomization. Results Statistically significant shorter time to healing (ulcer complete healing or satisfactory clinical improvement) between both groups (56 patients, 90.3% of cases in Group A versus 44 patients 77.2% of cases in Group B) over the follow-up period of 24 months was attained ( p = 0.001). Also, significantly different ulcer recurrence was recorded between both groups, 8 patients (12.9%) in Group A versus 19 patients (33.3%) in Group B ( p = 0.004). Conclusion In absence of deep venous obstruction, the monopolar radiofrequency ablation for incompetent perforators is a feasible and effective method that surpasses the traditional compression protocol for incompetent perforator-induced venous ulcers in terms of time required for healing even in the presence of unresolved deep venous valvular reflux. |
| Databáze: | OpenAIRE |
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