Epithelial hyperplasia of the larynx a clinical follow-up study
| Autor: | Yoshihumi Uno, Ryusuke Saito, Soichiro Nose, Kazuo Hamaya |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Larynx Pathology medicine.medical_specialty Hyperkeratosis Epithelium Biopsy medicine Humans Parakeratosis Laryngeal Neoplasms Aged Cell Line Transformed Retrospective Studies Hyperplasia medicine.diagnostic_test business.industry Incidence Carcinoma in situ Retrospective cohort study General Medicine Middle Aged medicine.disease Dyskeratosis Cell Transformation Neoplastic medicine.anatomical_structure Otorhinolaryngology Dysplasia Female Surgery medicine.symptom business Precancerous Conditions Follow-Up Studies |
| Zdroj: | Auris Nasus Larynx. 24:309-314 |
| ISSN: | 0385-8146 |
| DOI: | 10.1016/s0385-8146(96)00038-7 |
| Popis: | In this retrospective study, the records of 40 patients with epithelial hyperplasia of the larynx, seen between 1980-1991, were reviewed to determine the incidence of malignant transformation during long term follow-up. The mean follow-up time was 58.6 months. The initial pathological diagnoses were hyperkeratosis in one case, parakeratosis in one, dyskeratosis in 12 and dysplasia in 26. During follow up, nine patients developed carcinoma in situ and/or invasive carcinoma. Of these, two patients had been diagnosed with dyskeratosis without dysplastic cells at the initial biopsy. It is therefore important to follow up patients with epithelial hyperplasia of the larynx even when no dysplastic cells are found at the time of diagnosis. |
| Databáze: | OpenAIRE |
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