Structural basis of DNA recognition of tomato yellow leaf curl virus replication-associated protein

Autor: Chaonan, Wang, Shilong, Fan, Ning, Xu, Zhihong, Li, Senyan, Zhang, Shuifang, Zhu
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Biological Macromolecules. 205:316-328
ISSN: 0141-8130
Popis: Conserved and multifunctional Geminivirus Replication-associated Protein (Rep) specifically recognizes the replication origin and initiates viral DNA replication. We report the X-ray crystallography-based structures of two complexes containing the N-terminal domain (5-117aa) of Tomato yellow leaf curl virus (TYLCV) Rep: the catalytically-dead Rep in complex with nonanucleotide ssDNA (Rep
Databáze: OpenAIRE