Danger of amiodarone therapy and elevated inspired oxygen concentrations in mice
| Autor: | Jay Tappe, Stephen K. Donica, Thomas H. Swygert, Michael A. E. Ramsay, B.Roy Simpson, A. William Paulsen, Clark T. Saunders |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Vasodilator Agents Amiodarone Mice Inbred Strains Pulmonary Edema Mice Internal medicine Edema medicine Animals Lung Chemotherapy business.industry Respiration Respiratory disease Oxygenation Pulmonary edema medicine.disease Oxygen medicine.anatomical_structure Toxicity Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents medicine.drug |
| Zdroj: | The American journal of cardiology. 77(1) |
| ISSN: | 0002-9149 |
| Popis: | In conclusion, our study showed a statistically significant incidence of pulmonary edema in mice receiving amiodarone and 100% oxygen. This finding, together with a variety of clinical reports, indicates that in patients receiving amiodarone therapy, FiO 2 should be maintained at the lowest possible level, consistent with adequate oxygenation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect