Cardiovascular and respiratory responses to microinjection of L-glutamate into the caudal pressor area in conscious and anesthetized rats
| Autor: | H.A. Futuro Neto, J. G. P. Pires, N.F. Silva, Ruy R. Campos |
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| Přispěvatelé: | Universidade Federal do Espírito Santo Centro Biomédico Departamento de Ciências Fisiológicas, FAESA Faculdade de Saúde de Vitória, Universidade Federal de São Paulo (UNIFESP) |
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Male
Respiratory rate Consciousness Microinjections Physiology Immunology Biophysics Glutamic Acid Biochemistry Urethane Basal (phylogenetics) Heart Rate Respiration Medicine Animals ventrolateral medulla General Pharmacology Toxicology and Pharmaceutics Respiratory system Rats Wistar Receptor Microinjection lcsh:QH301-705.5 caudal pressor area Medulla Oblongata lcsh:R5-920 Vasomotor business.industry General Neuroscience blood pressure Cell Biology General Medicine Rats Blood pressure lcsh:Biology (General) Anesthesia L-glutamate business lcsh:Medicine (General) Anesthetics Intravenous respiration |
| Zdroj: | Repositório Institucional da UNIFESP Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP Brazilian Journal of Medical and Biological Research, Vol 34, Iss 12, Pp 1603-1606 (2001) Brazilian Journal of Medical and Biological Research, Volume: 34, Issue: 12, Pages: 1603-1606, Published: DEC 2001 |
| Popis: | The role of the caudal pressor area (CPA) in the maintenance of vasomotor tonus in anesthetized and decerebrate animals has been clearly established. In conscious animals, however, the participation of CPA in the cardiovascular control remains to be fully elucidated. In the present study, unilateral L-glutamate (L-Glu) (10 and/or 20 nmol/70 nl) microinjection into CPA, in conscious male Wistar rats (250-280 g) caused a significant increase in mean arterial blood pressure (MAP; control: 112 ± 1.9 mmHg; after 20 nmol L-Glu: 139 ± 4.5 mmHg, N = 12, P |
| Databáze: | OpenAIRE |
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