Significant reduction in the density of premature ventricular complex with ß-blocker medication in fast rate-dependent premature ventricular complex

Autor: Mi-Seung Shin, In Suck Choi, Woong Chol Kang, Chang Yun Kim, Yae Min Park, Seung Hwan Han, Mi Sook Cha, Albert Youngwoo Jang, Jungduk Seo
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Arrhythmia, Vol 21, Iss 1, Pp 1-8 (2020)
ISSN: 2466-1171
DOI: 10.1186/s42444-020-00028-2
Popis: Background There is little data regarding types of idiopathic premature ventricular complex (PVC) according to heart rate dependence. Methods One hundred and sixty-eight patients with idiopathic PVC were enrolled in this study. Evaluation of the number of PVCs and total ventricular beats, and the density of PVC was done using 24 h Holter monitoring. Patients were divided into groups as having: fast rate-dependent (Group I), slow rate-dependent (Group II), and heart rate-independent PVC (Group III) based on the relationship between the number of hourly PVC and hourly heart rate. After ß-blocker medication, 24 h Holter monitoring was repeated. Results Among the 168 subjects, 66 (39.3%) patients were in Group I, 18 (10.7%) in Group II, and 84 (50.0%) in Group III. There were no significant differences in the baseline number of PVCs and total ventricular beats, and the density of PVC among the three groups. The number of PVCs was significantly reduced in patients with Group I (14,030 ± 11,463 beats/day vs. 7401 ± 10,464 beats/day, p p p p = 0.001) after ß-blocker medication. Conclusions The type of PVC according to the heart rate dependence should be considered when treating idiopathic PVC with ß-blockers.
Databáze: OpenAIRE