Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care
| Autor: | Brygida Jaskot, Tomasz Miazgowski, Magdalena Kuczyńska, Maria Beata Czeszyńska, Zbigniew Celewicz, Jarosław Ogonowski |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Birth weight Population Type 2 diabetes Weight Gain White People Fetal Macrosomia Endocrinology Pregnancy Risk Factors Diabetes mellitus Internal Medicine Fetal macrosomia medicine Birth Weight Humans education Retrospective Studies Glycated Hemoglobin education.field_of_study Obstetrics business.industry Infant Newborn Pregnancy Outcome nutritional and metabolic diseases General Medicine medicine.disease female genital diseases and pregnancy complications Gestational diabetes Diabetes Gestational Small for gestational age Female Poland business |
| Zdroj: | Diabetes Research and Clinical Practice. 80:405-410 |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2008.01.017 |
| Popis: | Aims The aim of study was to assess the impact of intensive diabetic care, defined as target values for fasting glucose of 60–90mg/dl and 1-h postprandial glucose of below 130mg/dl, on neonatal birth weight in relation to risk indicators for fetal macrosomia in women with gestational diabetes mellitus (GDM). Methods In women with ( N =543) and without GDM ( N =1011) age, height, weight, previous GDM, history of macrosomia, family history of type 2 diabetes, parity and weight gain during pregnancy were recorded. Results Neonatal birth weight and frequency distribution of macrosomia and infants with small for gestational age did not differ between women with and without GDM. Neonatal birth weight was strongly associated with traditional risk predictors for GDM, such like prior macrosomia (OR 5.03; 95%CI 3.36–7.53), prior GDM (OR 2.52; 95%CI 1.37–4.64) and prepregnancy body mass index (BMI)>23kg/m 2 (OR 1.82; 95%CI 1.27–2.63). Conclusions Neonatal birth weight and the incidence of macrosomia were similar in comparison of pregnancies with and without GDM. In the population of Caucasian women the strongest single predictors for macrosomia were prior macrosomia, BMI>23kg/m 2 and prior GDM. |
| Databáze: | OpenAIRE |
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