Ileal Neuroendocrin Tumor Metastasis to Breast Diagnosed with Ga-68 DOTATATE PET/CT
| Autor: | Savas Karyagar, Sevda Sağlampınar Karyağar, Osman Güven |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
well differentiated neuroendocrin tumor
lcsh:Medical physics. Medical radiology. Nuclear medicine Pathology medicine.medical_specialty breast metastasis Proliferation index lcsh:R895-920 lcsh:Medicine Ileum Breast metastasis 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences 0302 clinical medicine Biopsy medicine Radiology Nuclear Medicine and imaging Ga-68 DOTATATE PET/CT lcsh:R5-920 PET-CT medicine.diagnostic_test business.industry lcsh:R medicine.disease Left breast medicine.anatomical_structure 030220 oncology & carcinogenesis Interesting Image lcsh:Medicine (General) Somatostatin analog business |
| Zdroj: | Molecular Imaging and Radionuclide Therapy, Vol 28, Iss 3, Pp 129-131 (2019) Molecular Imaging and Radionuclide Therapy |
| ISSN: | 2147-1959 2146-1414 |
| DOI: | 10.4274/mirt.galenos.2019.28199 |
| Popis: | Breast metastasis of the well differentiated neuroendocrin tumor (WDNET) of the ileum is very rare. A case of a 62-year-old woman with ileal WDNET, who underwent restaging with Ga-68 DOTATATE PET/CT due to progression of metastatic lesions under the treatment with somatostatin analog and mammalian target of rapamycin inhibitors. Ga-68 DOTATATE PET/CT demonstrated intense increased uptake in the subsantimetric nodular lesion in the upper outer quadrant of the left breast. The histopathologic findings obtained by tru-cut biopsy revealed WDNET metastasis (Ki-67 proliferation index 1%).İyi diferansiye ileal nöroendokrin tümör (NET) meme metastazı oldukça nadirdir. Altmış iki yaşında iyi diferansiye NET tümör tanılı kadın hastaya, metastatik lezyonlarının somatostatin analoğu ve rapamisinin memeli hedefi inhibitörleri ile tedavi görmekte iken progrese olması nedeniyle yeniden evreleme amacıyla Ga-68 DOTATATE PET/BT görüntüleme yapıldı. Ga-68 DOTATATE PET/BT görüntülemede, sol meme üst dış kadrandaki subsantimetrik nodüler lezyonda yoğun artmış aktivite tutulumu izlendi. Lezyondan yapılan tru-cut biyopsinin histopatolojik incelemesinde iyi diferansiye NET metastazı olduğu tespit edildi (Ki-67 proliferasyon indeksi %1). |
| Databáze: | OpenAIRE |
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