Análisis estadístico de la influencia del virus del papiloma humano en el desarrollo del carcinoma vesical
| Autor: | V. López León, M. Arrabal Martín, A. Zuluaga Gómez, A. Jiménez Pacheco, J. L. Martínez Torres, M. Pareja Vilchez, F. Valle Diaz de La Guardiã |
|---|---|
| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Actas Urológicas Españolas v.31 n.5 2007 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| ISSN: | 0210-4806 |
| DOI: | 10.1016/s0210-4806(07)73669-0 |
| Popis: | STATISTICAL ANALYSIS OF THE INFLUENCE OF THE VIRUS OF PAPILOMA HUMAN IN THE DEVELOPMENT OF THE VESICAL CARCINOMA Introduction: The bladder cancer is an important disease by its morbi-mortality and its multifactorialidad. At the moment, between the possible aetiology agents that they have been indicated is the infection by the virus of papilloma human (VPH). The objective study is to analyse, by meta-analysis, the relationship between bladder cancer and infection by human papillomavirus Material and methods: We made a search in the electronic data base MEDLINE of the articles published until September of the 2004 that relate the infection of the VPH to the bladder tumors. Of 414 listed articles, we selected 38 articles. Results: The articles were classified in two groups, according to they use or non methods based on the detection of the DNA. In articles based on the detection of the DNA, it was that the global proportion from the cases that had contact with the virus, through the detection of the genome was of the 19.4% (95% CI 0.160 to 0.228). Of the total of studies based on the detection of the DNA 8 were selected, to show to a group defined control, in which, the OR was investiga- ted. If we combined the ORs, we obtain an OR estimation of 3.2 (95% CI 1.19 to 8.60) and p=0.02. Conclusions: Most of these studies showed the relation rose at the beginning of the study. Although the majority lacked a group defined control, is possible to analyze the value of the Odds global ratio due to the homogenous behaviour of the stu- dies with defined cases and controls affluent. This demonstrated to association between VPH and the bladder cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|