Effect of Intensive Versus Standard Blood Pressure Control on Stroke Subtypes

Autor: Jeffrey T. Bates, James F. Meschia, James J Willard, Alan J. Lerner, Suzanne Oparil, Jerry Yee, Mary Ellen Sweeney, Vasilios Papademetriou, Anjay Rastogi, Clinton B. Wright, Jing Chen, Walter T. Ambrosius, Alexander P. Auchus, Suchita S. Pancholi, Hakan Ay
Rok vydání: 2021
Předmět:
Zdroj: Hypertension
ISSN: 1524-4563
0194-911X
DOI: 10.1161/hypertensionaha.120.16027
Popis: In the SPRINT (Systolic Blood Pressure Intervention Trial), the number of strokes did not differ significantly by treatment group. However, stroke subtypes have heterogeneous causes that could respond differently to intensive blood pressure control. SPRINT participants (N=9361) were randomized to target systolic blood pressures of P =0.09). The interaction between baseline cardiovascular risk factor status and treatment arm on stroke risk did not reach significance ( P =0.05). Similar numbers of stroke subtypes occurred in the intensive BP control and standard control arms of SPRINT.
Databáze: OpenAIRE