Kinetics of Trichloroethylene Elimination from Venous Blood After Acute Inhalation Poisoning
| Autor: | Przemyslaw Kostrzewski, Zbigniew Kolaciński, Marek Jakubowski |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Chromatography Gas Inhalation Trichloroethylene business.industry Health Toxicology and Mutagenesis Urinary system Poison control Venous blood Toxicology chemistry.chemical_compound chemistry Occupational Exposure Anesthesia Administration Inhalation Toxicity Humans Toxicokinetics Medicine Trichloroacetic Acid Trichloroacetic acid business Half-Life |
| Zdroj: | Journal of Toxicology: Clinical Toxicology. 31:353-363 |
| ISSN: | 0731-3810 |
| DOI: | 10.3109/15563659309000403 |
| Popis: | The kinetics of trichloroethylene were examined in three men, 28—36 years old, hospitalized after an acute occupational exposure. The trichloroethylene concentration of venous blood was determined by gas chromatography with headspace analysis; urinary trichloroacetic acid was assayed by the colorimetric method of Fujiwara. The kinetics of blood trichlorethylene (t1/2 21.7 h) and the urinary elimination of trichloracetic acid over six days were used to calculate the total inhalation exposures. Blood trichlorethylene was diagnostically more relevant than urinary trichloracetic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|