Fitness, strength and severity of COVID-19: a prospective register study of 1 559 187 Swedish conscripts
Autor: | Josefina Robertson, Jenny Nyberg, Lauren Lissner, Agnes Af Geijerstam, Annika Rosengren, Martin Adiels, Mats Börjesson, Maria A I Åberg, Kirsten Mehlig |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Adolescent Epidemiology Physical fitness Population 030204 cardiovascular system & hematology Body Mass Index Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Intensive care medicine Humans Muscle Strength 030212 general & internal medicine education Sweden education.field_of_study SARS-CoV-2 business.industry public health COVID-19 Cardiorespiratory fitness General Medicine Blood pressure Physical Fitness Medicine business Body mass index Cohort study |
Zdroj: | BMJ Open BMJ Open, Vol 11, Iss 7 (2021) |
ISSN: | 2044-6055 |
Popis: | ObjectiveTo investigate the possible connection between cardiorespiratory fitness (CRF) and muscle strength in early adulthood and severity of COVID-19 later in life.DesignProspective registry-based cohort study.Participants1 559 187 Swedish men, undergoing military conscription between 1968 and 2005 at a mean age of 18.3 (SD 0.73) years.Main outcome measuresHospitalisation, intensive care or death due to COVID-19 from March to September 2020, in relation to CRF and muscle strength.ResultsHigh CRF in late adolescence and early adulthood had a protective association with severe COVID-19 later in life with OR (95% CI) 0.76 (0.67 to 0.85) for hospitalisation (n=2 006), 0.61 (0.48 to 0.78) for intensive care (n=445) and 0.56 (0.37 to 0.85) for mortality (n=149), compared with the lowest category of CRF. The association remains unchanged when controlled for body mass index (BMI), blood pressure, chronic diseases and parental education level at baseline, and incident cardiovascular disease before 2020. Moreover, lower muscle strength in late adolescence showed a linear association with a higher risk of all three outcomes when controlled for BMI and height.ConclusionsPhysical fitness at a young age is associated with severity of COVID-19 many years later. This underscores the necessity to increase the general physical fitness of the population to offer protection against future viral pandemics. |
Databáze: | OpenAIRE |
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