A literature review on the role of chemical sphincterotomy after Milligan-Morgan hemorrhoidectomy
| Autor: | Arun Shangumanandan, Ian Swift, Muhammad Rafay Sameem Siddiqui, Chuk Abraham-Igwe, Veronica Grassi, Al Mutaz Abulafi |
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| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Botulinum Toxins genetic structures Anorectal disease Health Planning Guidelines Anal Canal Hemorrhoids Botulinum toxin a Nitroglycerin Postoperative Complications Medicine Humans Digestive System Surgical Procedures Pain Measurement Randomized Controlled Trials as Topic Wound Healing Milligan morgan business.industry Gastroenterology medicine.disease Calcium Channel Blockers Surgery Analgesia business Venous disease |
| Zdroj: | International journal of colorectal disease. 26(6) |
| ISSN: | 1432-1262 |
| Popis: | A literature review of agents used to induce chemical sphincterotomy after hemorrhoidectomy.Electronic databases were searched from January 1935 to August 2010.Two randomized controlled trials compared calcium channel blockers (Ca2) with placebo. Pain appeared to be less for up to 7 days, and its side-effect profile was comparable to the control group. Four randomized controlled trials examined the role of glyceryl trinitrate (GTN). GTN may be used up to 6 weeks to aid healing. Pain may be slightly less during its use and potentially offers less pain during defecation in the first 48 h. Its side-effect profile including headache appears comparable to placebo. Three randomized controlled trials investigated botulinum toxin A (BTX). BTX may be used to aid healing after hemorrhoidectomy. Pain may be less for up to a week after surgery. Its side-effect profile including incontinence to flatus appears comparable to placebo. It would be especially useful in cases where poor patient compliance is envisaged. Only one paper was found comparing BTX with GTN. BTX may be preferred over GTN due to better pain control and fewer side effects.BTX, Ca2, and GTN may give effective pain relief for a week after hemorrhoidectomy. Their side-effect profiles are comparable to placebo. |
| Databáze: | OpenAIRE |
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