Evidence for the Contribution of LTR Retrotransposons to C. elegans Gene Evolution
| Autor: | Vikram Bhattacharjee, Paul Schliekelman, Eric W. Ganko, John F. McDonald |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Retroelements
viruses Upstream and downstream (transduction) genetic processes Retrotransposon Evolution Molecular Exon Genetics Animals Caenorhabditis elegans Molecular Biology Gene Ecology Evolution Behavior and Systematics Models Statistical Models Genetic biology fungi Terminal Repeat Sequences Intron food and beverages Chromosome Exons biology.organism_classification Biological Evolution Introns health occupations Gene evolution |
| Zdroj: | Molecular Biology and Evolution. 20:1925-1931 |
| ISSN: | 1537-1719 0737-4038 |
| DOI: | 10.1093/molbev/msg200 |
| Popis: | LTR retrotransposons may be important contributors to host gene evolution because they contain regulatory and coding signals. In an effort to assess the possible contribution of LTR retrotransposons to C. elegans gene evolution, we searched upstream and downstream of LTR retrotransposon sequences for the presence of predicted genes. Sixty-three percent of LTR retrotransposon sequences (79/124) are located within 1 kb of a gene or within gene boundaries. Most gene-retrotransposon associations were located along the chromosome arms. Our results are consistent with the hypothesis that LTR retrotransposons have contributed to the structural and/or regulatory evolution of genes in C. elegans. |
| Databáze: | OpenAIRE |
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