High dose intravenous steroid therapy for severe posterior segment uveitis in Behçet's disease
| Autor: | Nur Acar, Haluk Kazokoglu, Ebru Toker |
|---|---|
| Přispěvatelé: | Toker, E, Kazokoglu, H, Acar, N |
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Systemic disease PROGNOSIS genetic structures Adolescent Eye disease Anti-Inflammatory Agents Retinitis Administration Oral Behcet's disease macromolecular substances Methylprednisolone Cellular and Molecular Neuroscience Medicine Humans PULSE METHYLPREDNISOLONE THERAPY Infusions Intravenous business.industry Behcet Syndrome Uveitis Posterior Middle Aged medicine.disease eye diseases Sensory Systems Surgery Posterior segment of eyeball Ophthalmology medicine.anatomical_structure Treatment Outcome Female Choroid business Vasculitis Uveitis Scientific Correspondence |
| Popis: | Aim: To evaluate the safety and effectiveness of high dose intravenous steroid therapy (HDIST) in Behcet's disease patients with severe posterior segment uveitis attacks. Methods: Five patients with ocular Behcet's disease were treated with HDIST for severe posterior segment attacks. Two patients had vasculitis, one patient had papillitis, and the other two had retinitis; four patients also had accompanying severe vitritis. The visual acuities and improvement in ocular signs after HDIST were evaluated. Results: During HDIST, patients had no systemic complications caused by treatment. All patients responded to HDIST with evidence of a decrease in intraocular inflammatory activity and improved visual acuities within a mean time of 7 (1–15) days of commencing treatment. During follow up three out of five patients had new posterior segment attacks. Conclusion: HDIST is effective in controlling severe, vision threatening acute posterior segment Behcet's uveitis attacks and in improving visual function in a short period of time |
| Databáze: | OpenAIRE |
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