Quantitative assessment of posture in healthy controls and patients with Parkinson's disease
| Autor: | Nils G. Margraf, Robin Wolke, Christian Schlenstedt, Oliver Granert, Günther Deuschl, Kathrin Boße, Olga Gavriliuc |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Future studies Parkinson's disease Intraclass correlation Posture Spinal Curvatures Age and gender Muscular Atrophy Spinal 03 medical and health sciences Camptocormia 0302 clinical medicine Physical medicine and rehabilitation Sex Factors medicine Quantitative assessment Humans Axial symptoms Aged business.industry Age Factors Parkinson Disease Middle Aged medicine.disease 030104 developmental biology Neurology Disease Progression Forward bending Female Neurology (clinical) Geriatrics and Gerontology business 030217 neurology & neurosurgery |
| Zdroj: | Parkinsonismrelated disorders. 76 |
| ISSN: | 1873-5126 |
| Popis: | A stooped posture is a main clinical feature of Parkinson's disease (PD). The assessment of posture is important to measure treatment effects. The aim of this study was to investigate the reliability of a standardized postural rating tool, to calculate minimal detectable change scores and to assess the role of gender and age.Two independent raters assessed total camptocormia (TCC), upper camptocormia (UCC) and Pisa angles of 192 PD patients and 78 healthy controls (HC) with the free NeuroPostureApp©(http://www.neuroimaging.uni-kiel.de/NeuroPostureApp). Reliabilities and linear models were calculated for different effects. Three subgroups were defined based on two thresholds (mean+2SD of HC and PD): A) normal, B) presumed stooped/lateral bended posture and C) postural disorder.Intraclass correlation coefficients ranged between 0.71 and 0.95 for the interrater and test-retest reliability of the three angles. The minimal detectable change values in the PD patients were 3.7°, 6.7° and 2.1° for the TCC, UCC and Pisa angles, respectively. Men had a more stooped posture than women (p 0.05). Patients with PD had a worse posture than HC (p 0.001) in all three angles. For the TCC angle, 39.1% of the patients had a normal posture (17.4°), 47.9% a presumed stooped posture (17.4°,30.2°) and 6.3° had camptocormia (30.2°).The NeuroPostureApp© is reliable. Our results confirmed gender differences and the progression of postural deviation in PD patients with age and empirically support the ≥30° TCC angle as a defining criterium for camptocormia. Diagnostic criteria for UCC and Pisa syndrome should be further explored in future studies. |
| Databáze: | OpenAIRE |
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