Investigating olfactory behaviors in adult zebrafish
| Autor: | Florence Kermen, Jack Bechert, Fabrizio Palumbo, Lea Darnet, Christoph Wiest, Emre Yaksi, Ozge Uslu |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
Future studies biology musculoskeletal neural and ocular physiology biology.organism_classification 03 medical and health sciences 0302 clinical medicine Ethogram Odor Fish Predator avoidance Mating Neuroscience Zebrafish psychological phenomena and processes 030217 neurology & neurosurgery 030304 developmental biology |
| DOI: | 10.1101/859033 |
| Popis: | Odor-driven behaviors such as feeding, mating and predator avoidance are crucial for animal survival. While the zebrafish olfactory circuitry is well understood, a comprehensive description of odor-driven behaviors is needed to better relate olfactory computations to animal responses. Here, we used a medium-throughput setup to measure the swimming trajectories of 10 zebrafish in response to 17 ecologically relevant odors. By selecting appropriate locomotor metrics, we constructed ethograms systematically describing odor-induced changes in the swimming trajectory. We found that fish reacted to most odorants, using different behavioral programs and that combination of few relevant behavioral metrics enabled to capture most of the variance in these innate odor responses. We observed that monomolecular odors in similar chemical categories were weakly clustered based on the behavioral responses, likely because natural odors elicited stronger reactions than the monomolecular odors. Finally, we uncovered a previously undescribed intra and inter-individual variability of olfactory behaviors and suggest a small set of odors that elicit robust responses. In conclusion, our setup and results will be useful resources for future studies interested in characterizing olfactory responses in aquatic animals. |
| Databáze: | OpenAIRE |
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