Two New 2-Arylbenzofuran Derivatives from Hypoglycemic Activity-Bearing Fractions of Morus insignis
| Autor: | Tsuneo Namba, Mineo Shimizu, Shigetoshi Kadota, Satoshi Terashima, Purusotam Basnet |
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| Rok vydání: | 1993 |
| Předmět: |
Blood Glucose
Male food.ingredient Ethyl acetate Pharmacognosy Diabetes Mellitus Experimental law.invention Rats Sprague-Dawley chemistry.chemical_compound food Glucosides Ursolic acid law Stilbenes Drug Discovery Botany medicine Animals Humans Hypoglycemic Agents Benzofurans Plants Medicinal Traditional medicine biology Chemistry Biological activity Resorcinols General Chemistry General Medicine Moraceae biology.organism_classification Streptozotocin Rats Child Preschool Phytotherapy Morus insignis medicine.drug |
| Zdroj: | Chemical and Pharmaceutical Bulletin. 41:1238-1243 |
| ISSN: | 1347-5223 0009-2363 |
| Popis: | Ethyl acetate- and n-butanol-soluble fractions of the leaves of Morus insignis showed a significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2) and moracin M-3-O-beta-D-glucopyranoside (3) were isolated, along with six known compounds [beta-sitosterol, beta-sitosterol-3-O-beta-glucopyranoside, ursolic acid, moracin M (1), kaempferol-3-O-beta-glucopyranoside and quercetin-3-O-beta-glucopyranoside] and the structures of the new compounds were determined by spectroscopic and chemical methods. |
| Databáze: | OpenAIRE |
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