Neural correlates of verbal memory in youth with heavy prenatal alcohol exposure
| Autor: | Edward P. Riley, Eileen M. Moore, Sarah N. Mattson, Kenneth L. Jones, Jeffrey R. Wozniak, Elizabeth R. Sowell, Claire D. Coles, Lauren A. Gross, Julie A. Kable |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Cognitive Neuroscience Population Audiology Verbal learning Article 050105 experimental psychology Developmental psychology 03 medical and health sciences Behavioral Neuroscience Cellular and Molecular Neuroscience 0302 clinical medicine Memory Region of interest medicine Humans 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging Child education Memory Disorders Neural correlates of consciousness education.field_of_study Recall 05 social sciences Neuropsychology Brain Organ Size Magnetic Resonance Imaging Psychiatry and Mental health Neurology Fetal Alcohol Spectrum Disorders Speech Perception Female Neurology (clinical) Analysis of variance Verbal memory Psychology 030217 neurology & neurosurgery |
| Zdroj: | Brain Imaging and Behavior. 12:806-822 |
| ISSN: | 1931-7565 1931-7557 |
| DOI: | 10.1007/s11682-017-9739-2 |
| Popis: | Prenatal alcohol exposure can impact both brain development and neurobehavioral function, including verbal learning and recall, although the relation between verbal recall and brain structure in this population has not been examined fully. We aimed to determine the structural neural correlates of verbal learning and recall in youth with histories of heavy prenatal alcohol exposure using a region of interest (ROI) approach. As part of an ongoing multisite project, subjects (age 10-16 years) with prenatal alcohol exposure (AE, n = 81) and controls (CON, n = 81) were tested using the CVLT-C and measures of cortical volume, surface area, and thickness as well as hippocampal volume were derived from MRI. Group differences in brain and memory indices were tested with ANOVA. Multiple regression analyses tested whether brain ROIs significantly predicted memory performance. The AE group had lower scores than the CON group on all CVLT-C variables (ps ≤ .001) and volume and surface area (ps |
| Databáze: | OpenAIRE |
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