Hereditary gastric and pancreatic cancer predisposition syndromes
| Autor: | Ariadna Sánchez, Leticia Moreira, Maria Pellise, Maria Liz Leoz, Antoni Castells, Francesc Balaguer, Sabela Carballal, Lucía Ruano, Teresa Ocaña |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Risk Oncology medicine.medical_specialty Cystic Fibrosis Colorectal cancer Breast Neoplasms Adenocarcinoma Gastroenterology Familial adenomatous polyposis Neoplasms Multiple Primary 03 medical and health sciences 0302 clinical medicine Neoplastic Syndromes Hereditary Stomach Neoplasms Pancreatic cancer Internal medicine medicine Humans Genes Tumor Suppressor Genetic Predisposition to Disease Endoscopy Digestive System Melanoma Early Detection of Cancer Hereditary Pancreatic Cancer Ovarian Neoplasms business.industry Mortality rate Cancer medicine.disease Lynch syndrome Pancreatic Neoplasms 030220 oncology & carcinogenesis Mutation Female 030211 gastroenterology & hepatology Familial Cancer Colorectal Neoplasms business Forecasting Genes Neoplasm |
| Zdroj: | Gastroenterología y Hepatología (English Edition). 39:481-493 |
| ISSN: | 2444-3824 |
| DOI: | 10.1016/j.gastre.2016.06.010 |
| Popis: | The most common hereditary gastrointestinal cancers are colorectal, mainly hereditary nonpolyposis colorectal cancer (Lynch syndrome) and familial adenomatous polyposis. Other extracolonic neoplasms, including the gastric and pancreatic adenocarcinomas, are less well known and studied because they account for a relatively small percentage of hereditary gastrointestinal cancers. Nonetheless, they merit special attention because of the high associated morbidity and mortality rates. We review the hereditary and familial syndromes associated with gastric and pancreatic cancers with a view to improving knowledge and understanding of these diseases, in order to heighten diagnostic suspicion and thus implement appropriate diagnostic strategies, screening, surveillance and treatment. |
| Databáze: | OpenAIRE |
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