Complex Mandibular Reconstruction for Head and Neck Squamous Cell Carcinoma—The Ongoing Challenge in Reconstruction and Rehabilitation
Autor: | Wolfgang Zemann, Josip Tomic, Philipp Metzler, Mauro Pau, Matthias Feichtinger, Peter Valentin Tomazic, Tomislav Zrnc, Hamid Hassanzadeh |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
N43
Cancer Research medicine.medical_specialty EORTC QLQ-H& surgical treatment Free flap head and neck squamous cell carcinoma lcsh:RC254-282 HNSCC Article 03 medical and health sciences 0302 clinical medicine Quality of life medicine.artery prosthetic rehabilitation Medicine free flap business.industry Mandible mandible composite reconstruction Cancer Retrospective cohort study EORTC QLQ-C30 030206 dentistry Angular artery lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Head and neck squamous-cell carcinoma humanities medicine.anatomical_structure Oncology quality of life 030220 oncology & carcinogenesis EORTC QLQ-H&N43 Radiology business Artery |
Zdroj: | Cancers Volume 12 Issue 11 Cancers, Vol 12, Iss 3198, p 3198 (2020) |
ISSN: | 2072-6694 |
DOI: | 10.3390/cancers12113198 |
Popis: | Large head and neck squamous cell carcinoma (HNSCC) tumors affecting the mandible require a versatile reconstruction to maintain form, function, and quality of life. Large defect reconstruction of soft and hard tissue in the head and neck necessitates, at best, one vascular system including various tissues by large dimensions. The subscapular flap system seems to meet these standards. A retrospective study was conducted focusing on clinical data, including an analysis of the quality of life with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaires, (QLQ-C30 and QLQ-H& N43). A total of 154 patients (122 males, 32 females age range: 31&ndash 71 years, mean: 54.5 years) treated at our department from 1983 through to 2019 were included. Of the subscapular system free flaps (SFFs), 147 were based on the angular artery branch of the thoracodorsal pedicle (95.45%), and the remaining seven cases (4.55%) were lateral scapular border flaps. Mean mandible defect length was 7.3 cm. The mean skin paddle dimension was 86.8 cm2. The most common recipient artery was the thyroid superior artery (79.22%). Major postoperative complications occurred in 13 patients (8.44%). This study confirms that SFFs offer excellent soft and hard tissue quality, component independence, a large arc of rotation length, and a large gauge of pedicle, making them the gold standard for the reconstruction of large composite defects of mandibular HNSCC tumors. |
Databáze: | OpenAIRE |
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