Nutritional factors influencing plasma adiponectin levels: results from a randomised controlled study with whole-grain cereals
| Autor: | Ersilia Nigro, Rosalba Giacco, Delia Luongo, Giuseppina Costabile, Rita Polito, Claudia Vetrani, Gabriele Riccardi, Gaia Anniballi, Giovanni Annuzzi, Aurora Daniele |
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| Přispěvatelé: | Polito, Rita, Costabile, Giuseppina, Nigro, Ersilia, Giacco, Rosalba, Vetrani, Claudia, Anniballi, Gaia, Luongo, Delia, Riccardi, Gabriele, Daniele, Aurora, Annuzzi, Giovanni |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Adult Dietary Fiber Male medicine.medical_specialty 030209 endocrinology & metabolism Plasma adiponectin Gut flora 03 medical and health sciences Plasma 0302 clinical medicine Internal medicine medicine postprandial metabolism Humans Adiponectin dietary fibre metabolic syndrome short-chain fatty acids whole-grain cereals Whole Grain Cereals Diet Fat-Restricted Aged Metabolic Syndrome Whole Grains 030109 nutrition & dietetics biology business.industry food and beverages Fasting Anthropometry Middle Aged medicine.disease biology.organism_classification Fatty Acids Volatile Postprandial Period Intervention studies Gastrointestinal Microbiome Postprandial Endocrinology Glycemic Index Female Metabolic syndrome short-chain fatty acid business Edible Grain Energy Intake whole-grain cereal Food Science |
| Zdroj: | International journal of food sciences and nutrition (2019). doi:10.1080/09637486.2019.1680959 info:cnr-pdr/source/autori:Polito R.; Costabile G.; Nigro E.; Giacco R.; Vetrani C.; Anniballi G.; Luongo D.; Riccardi G.; Daniele A.; Annuzzi G./titolo:Nutritional factors influencing plasma adiponectin levels: results from a randomised controlled study with whole-grain cereals/doi:10.1080%2F09637486.2019.1680959/rivista:International journal of food sciences and nutrition/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume |
| ISSN: | 0094-5854 |
| DOI: | 10.6084/m9.figshare.10023035 |
| Popis: | Data from intervention studies about the effects of a high intake of whole-grain cereals on adiponectin expression are still inconclusive. We evaluated the effects of whole-grain or refined cereals on fasting and postprandial serum adiponectin in people at high cardiovascular risk. According to a randomised controlled parallel group design, participants with metabolic syndrome were assigned to an isoenergetic diet based on either whole-grain cereal (WGC) or refined cereal (RC) products for 12-weeks. Anthropometric and biochemical measures were taken. Compared to baseline, fasting and postprandial serum adiponectin levels increased after both RC and WGC. In the WGC and RC groups combined, adiponectin concentrations significantly increased after 12-week intervention, and are directly associated with plasma SCFAs and acetate. Only increasing whole-grain cereals may not influence adiponectin levels, which could be modified by a fibre rich, low-fat, low-glycemic index diet, possibly through changes in gut microbiota, as suggested by the relation with SCFAs. Clinical Trials number: NCT00945854. Data from intervention studies about the effects of a high intake of whole-grain cereals on adiponectin expression are still inconclusive. We evaluated the effects of whole-grain or refined cereals on fasting and postprandial serum adiponectin in people at high cardiovascular risk. According to a randomised controlled parallel group design, participants with metabolic syndrome were assigned to an isoenergetic diet based on either whole-grain cereal (WGC) or refined cereal (RC) products for 12-weeks. Anthropometric and biochemical measures were taken. Compared to baseline, fasting and postprandial serum adiponectin levels increased after both RC and WGC. In the WGC and RC groups combined, adiponectin concentrations significantly increased after 12-week intervention, and are directly associated with plasma SCFAs and acetate. Only increasing whole-grain cereals may not influence adiponectin levels, which could be modified by a fibre rich, low-fat, low-glycemic index diet, possibly through changes in gut microbiota, as suggested by the relation with SCFAs. Clinical Trials number: NCT00945854. |
| Databáze: | OpenAIRE |
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