HLA serum screening based on an heuristic solution of the set cover problem

Autor:	D.B Amos, M.A Woodbury, E.A Ciftan
Rok vydání:	1979
Předmět:	Heuristic (computer science) Computers Histocompatibility Testing Immune Sera Medicine (miscellaneous) Set cover problem Human leukocyte antigen On cells Epitopes HLA Antigens Humans Serum screening NP-complete Algorithm Blood bank Mathematics
Zdroj:	Computer programs in biomedicine. 9(3)
ISSN:	0010-468X
Popis:	A computer program initially written by the Milwaukee Blood Bank has been modified to use a new algorithm for the assignment of HLA specificities to antisera. The assignment is based on the reactions of cells with known specificities. Specificities which are present only on cells which do not react are first ruled out. This step is followed by one or more steps in which the ‘least reactive’ specificities are ruled out. The rationale for the algorithm is discussed and an example is presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa22e3f35a41d9b6e3588be86fdee98e https://pubmed.ncbi.nlm.nih.gov/86406 Zobrazit plný text záznamu