Cerebral blood volume Alberta Stroke Program Early Computed Tomography Score predicts intracranial hemorrhage after thrombectomy in patients with acute ischemic stroke in an extended time window

Autor: Hai-Bin Shi, Sheng Liu, Lin-Bo Zhao, Xiao-Quan Xu, Zhen-Yu Jia, Qiang-Hui Liu, Yue-Zhou Cao
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Time Factors
Mechanical Thrombolysis
Asymptomatic
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Fibrinolytic Agents
Predictive Value of Tests
Internal medicine
Multidetector Computed Tomography
Confidence Intervals
medicine
Cerebral Blood Volume
Humans
Radiology
Nuclear Medicine and imaging
030212 general & internal medicine
Acute ischemic stroke
Stroke
Aged
Ischemic Stroke
Retrospective Studies
Analysis of Variance
Univariate analysis
Radiological and Ultrasound Technology
business.industry
Infarction
Middle Cerebral Artery
General Medicine
Odds ratio
medicine.disease
Recombinant Proteins
Confidence interval
Cerebral blood volume
Cerebrovascular Circulation
Tissue Plasminogen Activator
Acute Disease
Asymptomatic Diseases
Cardiology
Female
medicine.symptom
business
Intracranial Hemorrhages
Tomography
Spiral Computed
Perfusion
030217 neurology & neurosurgery
Zdroj: Acta Radiologica. 63:393-400
ISSN: 1600-0455
0284-1851
DOI: 10.1177/0284185121990843
Popis: Background Higher baseline Alberta Stroke Program Early Computed Tomography Score (ASPECTS) was associated with a lower probability of hemorrhagic transformation in patients with acute ischemic stroke (AIS). Purpose To investigate the predictive value of cerebral blood volume (CBV)-ASPECTS of intracranial hemorrhage (ICH) in AIS treated with thrombectomy selected by computed tomographic perfusion (CTP) in an extended time window. Material and Methods A total of 91 consecutive patients with AIS with large vessel occlusion in the anterior circulation after thrombectomy in an extended time window were enrolled between January 2018 and September 2019. ICH was diagnosed according to Heidelberg Bleeding Classification. CBV-ASPECTS was assessed by evaluating each ASPECTS region for relatively low CBV value compared with the mirror region in the contralateral hemisphere. Demographic characteristics, clinical data, CBV-ASPECTS, and procedure process and results were compared between patients with ICH and those without. Results ICH occurred in 31/91 (34.1%) patients with AIS. Symptomatic ICH (sICH) was observed in 4 (4.4%) patients, while asymptomatic ICH (aICH) was seen in 27 (29.7%). In univariate analysis, both ICH and aICH were associated with high admission NIHSS score ( PConclusion Low CBV-ASPECTS independently predicts ICH in patients with AIS treated with thrombectomy selected by CTP in an extended time window.
Databáze: OpenAIRE
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