Rapid Rise and Fall of Selfish Sex-Ratio X Chromosomes in Drosophila simulans: Spatiotemporal Analysis of Phenotypic and Molecular Data
| Autor: | Michel Cazemajor, Nicolas Derome, Héloïse Bastide, David Ogereau, Catherine Montchamp-Moreau |
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| Přispěvatelé: | Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), Génétique Animale et Biologie Intégrative (GABI), AgroParisTech-Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-AgroParisTech |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Male
0106 biological sciences [SDV.SA]Life Sciences [q-bio]/Agricultural sciences X Chromosome Population genetics sex-ratio Biology 010603 evolutionary biology 01 natural sciences Evolution Molecular selective sweep 03 medical and health sciences Intragenomic conflict Genes Duplicate natural population Genetics Animals Sex Ratio Molecular Biology Ecology Evolution Behavior and Systematics X chromosome Demography Repetitive Sequences Nucleic Acid 030304 developmental biology Segmental duplication 0303 health sciences Models Genetic Haplotype Chromosome meiotic drive drosophila simulans Meiosis Haplotypes Drosophila Selective sweep Sex ratio |
| Zdroj: | Molecular Biology and Evolution Molecular Biology and Evolution, Oxford University Press (OUP), 2011, 28 (9), pp.2461-2470. ⟨10.1093/molbev/msr074⟩ |
| ISSN: | 0737-4038 1537-1719 |
| Popis: | Chantier qualité GA; Sex-ratio drive, which has been documented in several Drosophila species, is induced by X-linked segregation distorters. Contrary to Mendel's law of independent assortment, the sex-ratio chromosome (XSR) is inherited by more than half the offspring of carrier males, resulting in a female-biased sex ratio. This segregation advantage allows XSR to spread in populations, even if it is not beneficial for the carriers. In the cosmopolitan species D. simulans, the Paris sex-ratio is caused by recently emerged selfish XSR chromosomes. These chromosomes have triggered an intragenomic conflict, and their propagation has been halted over a large area by the evolution of complete drive suppression. Previous molecular population genetics analyses revealed a selective sweep indicating that the invasion of XSR chromosomes was very recent in Madagascar (likely less than 100 years ago). Here, we show that XSR chromosomes are now declining at this location as well as in Mayotte and Kenya. Drive suppression is complete in the three populations, which display little genetic differentiation and share swept haplotypes, attesting to a common and very recent ancestry of the XSR chromosomes. Patterns of DNA sequence variation also indicate a fitness cost of the segmental duplication involved in drive. The data suggest that XSR chromosomes started declining first on the African continent, then in Mayotte, and finally in Madagascar and strongly support a scenario of rapid cycling of X chromosomes. Once drive suppression has evolved, standard XST chromosomes locally replace costly XSR chromosomes in a few decades. |
| Databáze: | OpenAIRE |
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