Generic ICD programming and outcomes

Autor: Nishat Jahagirdar, Edward Petzer, Antonio Cannatà, Paul A. Scott, Micaela Laybourn, Idris Harding, Parisha Khan, Husain Shabeeh, Francis Murgatroyd, Daniel I. Bromage, Peter Kabunga
Rok vydání: 2021
Předmět:
Zdroj: Pacing and clinical electrophysiology : PACEREFERENCES. 44(12)
ISSN: 1540-8159
Popis: INTRODUCTION Generic ICD programming, where shock-reduction programming is extrapolated from trials of one manufacturer to another, may reduce non-essential ICD therapies beyond that seen in randomized trials. However, the benefits and risks are unknown. The purpose of this retrospective cohort study was to evaluate the impact of a standardized programming protocol, based on generic programming, across manufacturers. METHODS We included all new ICDs in a single center (2009-2019). In 2013 a standardized programming protocol based on generic programming was introduced, incorporating high detection rates (200 bpm for primary prevention) and long detection (30/40 or equivalent in VF zone) for all patients. Patients were classified into three groups based on implant programming: pre-guideline (PS), post-guideline and guideline compliant (GC) and post-guideline but not guideline compliant (NGC). The end-points were the first occurrence of any device therapy (ATP or shock), ICD shock, syncope and all-cause mortality. Survival analysis was used to evaluate outcomes. RESULTS 1003 patients were included (mean follow-up 1519 ± 1005 days). In primary prevention patients (n = 583) freedom from ICD therapy (91.5% vs. 73.6%, p
Databáze: OpenAIRE
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