Quantitative evaluation of norcholesterol scintigraphy, CT attenuation value, and chemical-shift MR imaging for characterizing adrenal adenomas
| Autor: | Norio Tsuchiya, Yoshihiro Komeya, Teruaki Yoh, Taro Shimono, Yasumasa Nishimura, Takamichi Murakami, Ryuichiro Ashikaga, Makoto Hosono, Yukinobu Yagyu, Masahiro Okada, Sung-Woon Im, Kazushi Hanada |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Fat suppression Adrenal Gland Neoplasms Computed tomography Ct attenuation Scintigraphy Sensitivity and Specificity Image Interpretation Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging Uptake rate Aged Aged 80 and over medicine.diagnostic_test business.industry 19-Iodocholesterol Reproducibility of Results Magnetic resonance imaging General Medicine Middle Aged Mr imaging Magnetic Resonance Imaging Adrenocortical Adenoma Female Radiology Radiopharmaceuticals business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Annals of nuclear medicine. 22(6) |
| ISSN: | 0914-7187 |
| Popis: | The objective of our study was to evaluate diagnostic ability and features of quantitative indices of three modalities: uptake rate on norcholesterol scintigraphy, computed tomography (CT) attenuation value, and fat suppression on chemical-shift magnetic resonance imaging (MRI) for characterizing adrenal adenomas.Image findings of norcholesterol scintigraphy, CT, and MRI were reviewed for 78 patients with functioning (n = 48) or nonfunctioning (n = 30) adrenal masses. The norcholesterol uptake rate, attenuation value on unenhanced CT, and suppression on in-phase to opposed-phase MRI were measured for adrenal masses.The norcholesterol uptake rate, CT attenuation value, and MR suppression index showed the sensitivity of 60%, 82%, and 100%, respectively, for functioning adenomas of2.0 cm, and 96%, 79%, and 67%, respectively, for those ofor=2.0 cm. A statistically significant correlation was observed between size and norcholesterol uptake, and between CT attenuation value and MR suppression index. Regarding norcholesterol uptake, the adenoma-to-contralateral gland ratio was significantly higher in cortisol releasing than in aldosterone-releasing adenomas.The norcholesterol uptake rate was reliable for characterization of adenomas among adrenal masses ofor=2.0 cm. CT attenuation value and MR suppression index were well correlated with each other, and were useful regardless of mass size. |
| Databáze: | OpenAIRE |
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