Nanotechnology based strategies for HIV-1 and HTLV-1 retroviruses gene detection
| Autor: | Saber Soltani, Sayed-Hamidreza Mozhgani, Hanie Ahmadzade Kermani, Mehdi Norouzi, Mohsen Arabi |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Human T-cell lymphotropic virus (HTLV) Human immunodeficiency virus (HIV) DNA nanobiosensors Early detection Nanotechnology Biology medicine.disease_cause Article Virus 03 medical and health sciences 0302 clinical medicine medicine lcsh:Social sciences (General) lcsh:Science (General) Clinical treatment Gene Infectious disease Multidisciplinary 030104 developmental biology Infectious disease (medical specialty) Nucleic acid lcsh:H1-99 Biosensor Analytical chemistry 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Heliyon, Vol 6, Iss 5, Pp e04048-(2020) Heliyon |
| ISSN: | 2405-8440 |
| Popis: | Early detection of retroviruses including human T-cell lymphotropic virus and human immunodeficiency virus in the human body is indispensable to prevent retroviral infection propagation and improve clinical treatment. Until now, diverse techniques have been employed for the early detection of viruses. Traditional methods are time-consuming, resource-intensive, and laborious performing. Therefore, designing and constructing a selective and sensitive diagnosis system to detect serious diseases is highly demanded. Genetic detection with high sensitivity has striking significance for the early detection and remedy of disparate pathogenic diseases. The nucleic acid biosensors are based on the identification of specific DNA sequences in biological samples. Nanotechnology has an important impact on the development of sensitive biosensors. Different kinds of nanomaterials include nanoparticles, nanoclusters, quantum dots, carbon nanotubes, nanocomposites, etc., with different properties have been used to improve the performance of biosensors. Recently, DNA nanobiosensors are developed to provide simple, fast, selective, low-cost, and sensitive detection of infectious diseases. In this paper, the research progresses of nano genosensors for the detection of HIV-1 and HTLV-1 viruses, based on electrochemical, optical, and photoelectrochemical platforms are overviewed. Analytical chemistry; Infectious disease; Nanotechnology; Human immunodeficiency virus (HIV); Human T-cell lymphotropic virus (HTLV); Early detection; DNA nanobiosensors |
| Databáze: | OpenAIRE |
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