An extremely indolent T-cell leukemia: an 18-year follow-up
| Autor: | Adam Bagg, Dennis B. Cornfield, DO Nicole M Agostino, Samuel Adediran |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Lymphocytosis business.industry T-cell leukemia Clinical course Hematology Disease 030204 cardiovascular system & hematology Malignancy medicine.disease Dermatology Asymptomatic 03 medical and health sciences 0302 clinical medicine Oncology B symptoms 030220 oncology & carcinogenesis medicine medicine.symptom Prolymphocytic leukemia business |
| Zdroj: | The Journal of community and supportive oncology. 14(2) |
| ISSN: | 2330-7749 |
| Popis: | T-cell prolymphocytic leukemia (T-PLL) is a rare malignancy that comprises about 2% of all mature lymphoid neoplasms. Patients usually present with prominent peripheral blood lymphocytosis, splenomegaly, hepatomegaly, lymphadenopathy, B symptoms, and occasionally with skin lesions.¹ The disease follows an aggressive clinical course with rapid progression and typically has a median survival of less than 1 year. In some cases, the disease is indolent for a period of time before becoming aggressive.² In 2002, 7 years after initial diagnosis in 1995, the case discussed herein was reported as a rare, indolent form of T-PLL.³ We now present 11 additional years of follow-up of this case, during which time the patient remained asymptomatic with respect to his lymphoid neoplasm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|